When Tablet PCs were introduced people had to start thinking about portrait mode, which commonly had a minimum of 768x1024. Last year when Ultra-Mobile PCs were introduced people started thinking about how x480 impacts application design. Some of this year's UMPCs have portrait mode too, so now 480x and x480 are the minimum resolutions in which your application may be viewed.
So when you're designing the new version of your installer, news reader, rss feed reader, eBook reader, note taking app, task list, and anything else someone might be apt to rotate into portrait mode make sure you check 480x for the best user experience.
(P.S. Please pretend the above is a square. I know it's just off.)
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What Is New in Tablet PCs and UMPCs.