For a home user :

Avast Home - turn off unused shields.
Windows Defender
SmartScreen Filter (in IE8)
Run IE8 in Protected Mode and with InPrivate Filtering as the default
(registry entry)
Prevx 3.0 Free (you can add this with AVG also)
UAC on or in Quiet Mode
Windows Firewall
Set InPrivate Filtering at AUTO or Prompt and use the converted AdBlocker
File.
Windows UpDates ON however set Advanced System Settings - Hardware Tab -
Windows Update Driver Settings - Never Check for Drivers when I connect a
Device (always go to a device makers site and manually look for updated
drivers).

Even more secure would be to use InPrivate Browsing all the time.

The security built into Vista is so integrated that many programs just get
in the way.

Use SuperAntiSpyware and MalwareBytes as Scanners Only, nothing resident.
Though mine has never caught anything except an occasional cookie.

There are other scenarios however this one is extremely tight
"Eustace" <emfril******.com> wrote in message
news:%23Wo0kGV%23JHA.3544@TK2MSFTNGP04.phx.gbl...[color=blue]
>I just uninstalled the McAffee Security Center that came with my laptop and
>installed AVG antivirus instead. Is there anything else I need to do to
>complete the basic protection of my system?
>
> emf
>
> --
> It ain't THAT, babe! - A radical reinterpretation
> [url]http://www.geocities.com/itaintme_babe/itaintme.html[/url][/color]