runthe fixboot command.
there is info/instruct. on the command @ microsoft.com

"ens" <ens@discussions.microsoft.com> wrote in message
news:C24F045E-4F5B-4F6F-A020-7D823EAF7391@microsoft.com...
> Have been using a HD as secondary on computer with no problems. Got a new
> Computer and using the old main HD as secondary on new one. Have a slip
> streamed xp Pro sp2 cd. Trying to do a clean install on the HD I was
> using
> as secondary. Formatted for NTFS. Copies all the files, etc. then the
> ...will reboot in 14 seconds... goes thru that, but momentarily get the
> "press any key to boot from CD", then goes to:
>
> Couldn't open drive multi(0)disk(0)rdisk(0)partition(1)
> NTLDR: Couldn't open drive........... (same as above)
>
> What is causing this?
> Ernie